Research and Education

Scientific publishing

Research
Scientific publishing
2024
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2023

Characterisation of the protein expression of the emerging immunotherapy targets VISTA, LAG-3 and PRAME in primary uveal melanoma: insights from a southern French patient cohort.
Pathology

Lamas NJ, Lassalle S, Martel A, Nahon-Estève S, Macocco A, Zahaf K, Lalvee S, Fayada J, Lespinet-Fabre V, Bordone O, Pedeutour F, Baillif S, Hofman P.
 

2023 DEC;55(7):929-944

Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality.
Trends Mol Med

Guillot N, Roméo B, Manesh SS, Milano G, Brest P, Zitvogel L, Hofman P, Mograbi B.
 

2023 NOV;29(11):897-911

Optimizing tissue stewardship in non-small cell lung cancer to support molecular characterization and treatment selection: statement from a working group of thoracic pathologists.
Histopathology

Kerr KM, Bubendorf L, Lopez-Rios F, Khalil F, Roy-Chowdhuri S, Joubert P, Hartmann A, Guerini-Rocco E, Yatabe Y, Hofman P, Cooper WA, Dacic S.

 

2023 NOV 13
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2022

Accelerating the Development and Validation of Liquid Biopsy for Early Cancer Screening and Treatment Tailoring.
Healthcare (Basel).

Horgan D, Cufer T, Gatto F, Lugowska I, Verbanac D, Carvalho Â, Lal JA, Kozaric M, Toomey S, Ivanov HY, Longshore J, Malapelle U, Hasenleithner S, Hofman P, Alix-Panabières C.

2022 Sep 7;10(9):1714.
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2021

Correction: The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress.
Oncogene.

Leon LM, Gautier M, Allan R, Ilié M, Nottet N, Pons N, Paquet A, Lebrigand K, Truchi M, Fassy J, Magnone V, Kinnebrew G, Radovich M, Cheok MH, Barbry P, Vassaux G, Marquette CH, Ponzio G, Ivan M, Pottier N, Hofman P, Mari B, Rezzonico R.
 

2021 Apr;40(14):2621.

PD-L1 expression and immune cells infiltration in primary tracheobronchial neoplasm.
Transl Lung Cancer Res.

Zheng KF, Liu YJ, Ma N, Xiong YL, Tang XY, Zhang Q, Luo ZL, Tian HH, Hofman P, Ichiki Y, Metro G, Tachihara M, Gong L, Li XF, Zhao JB.

 

2021 Dec;10(12):4617-4630.

Detection of ALK fusion transcripts in plasma of non-small cell lung cancer patients using a novel RT-PCR based assay.
Ann Transl Med.

Heeke S, Benzaquen J, Vallee A, Allegra M, Mazieres J, Fayada J, Rajamani J, Lee M, Ordinario E, Tiotiu A, Cadranel J, Poudenx M, Moro-Sibilot D, Barlesi F, Gervais R, Thariat J, Tanga V, Boutros J, Ilié M, Hofman V, Marquette CH, Denis MG, Hofman P.

2021 Jun;9(11):922.
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2020

Mutational Profile Evaluates Response and Survival to First-Line Chemotherapy in Lung Cancer.
Adv Sci (Weinh)

He Y, Song L, Wang H, Chen P, Liu Y, Sun H, Li X, Dang S, Liu G, Liu X, Chen S, Zhang X, Hofman P, Uchino J, Park HS, Pacheco JM, Tabbò F, Xu M, Dai J, He K, Yang Y, Zhou C; written on behalf of the AME Lung Cancer Collaborative Group.

2020 Dec 30;8(4):2003263.
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2019
2019 Sep 1;30(9):1448-1459.

In-house Implementation of Tumor Mutational Burden Testing to Predict Durable Clinical Benefit in Non-small Cell Lung Cancer and Melanoma Patients. Cancers (Basel).

Heeke S, Benzaquen J, Long-Mira E, Audelan B, Lespinet V, Bordone O, Lalvée S, Zahaf K, Poudenx M, Humbert O, Montaudié H, Dugourd PM, Chassang M, Passeron T, Delingette H, Marquette CH, Hofman V, Stenzinger A, Ilié M, Hofman P.

2019 Aug 29;11(9).

DNAshell Protects DNA Stored at Room Temperature for Downstream Next-Generation Sequencing Studies. Biopreserv Biobank.

Washetine K, Heeke S, Ribeyre C, Bourreau C, Normand C, Blons H, Laurent-Puig P, Mulot C, Clermont D, David M, Clément B, Dagher G, Hofman P.

2019 Aug;17(4):352-354.
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2018

Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients. Lung Cancer.

Falk AT, Yazbeck N, Guibert N, Chamorey E, Paquet A, Ribeyre L, Bence C, Zahaf K, Leroy S, Marquette CH, Cohen C, Mograbi B, Mazières J, Hofman V, Brest P, Hofman P, Ilié M. 

2018 Jul;121:70-75.

Ensuring the Safety and Security of Frozen Lung Cancer Tissue Collections through the Encapsulation of Dried DNA. Cancers (Basel).

Washetine K, Kara-Borni M, Heeke S, Bonnetaud C, Félix JM, Ribeyre L, Bence C, Ilié M, Bordone O, Pedro M, Maitre P, Tanga V, Gormally E, Mossuz P, Lorimier P, Marquette CH, Mouroux J, Cohen C, Lassalle S, Long-Mira E, Clément B, Dagher G, Hofman V, Hofman P. 

2018 Jun 11;10(6).

Use of circulating tumor cells in prospective clinical trials for NSCLC patients – standardization of the pre-analytical conditions. Clin Chem Lab Med.

Ilie M, Hofman V, Leroy S, Cohen C, Heeke S, Cattet F, Bence C, Lalvée S, Mouroux J, Marquette CH, Hofman P; STALKLUNG01 and AIR Study Consortium Investigators.

2018 May 24;56(6):980-989.
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2017
2017 Dec;17(12):1097-1108

Training the Next Generation of Biobankers: A Two-Year Master ’s Course in the Management of Biobanks.  Biopreservation and Biobanking

Gormally E, Hardy I, Caboux E, di Donato JH, Hainaut P, Hofman P. 

2017 Oct;15(5):438-450

Optimization of EGFR mutation detection by the fully-automated PCR-based Idylla system on tumor tissue from patients with non-small cell lung cancer. Oncotarget.

Ilie M, Butori C, Lassalle S, Heeke S, Piton N, Sabourin JC, Tanga V, Washetine K, Long-Mira E, Maitre P, Yazbeck N, Bordone O, Lespinet V, Leroy S, Cohen C, Mouroux J, Marquette CH, Hofman V, Hofman P. 

2017 Oct 4;8(61):103055-103062
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2016

PD-L1 expression in basaloid squamous cell lung carcinoma:
Relationship to PD-1+ and CD8+ tumor-infiltrating T cells and outcome.
Modern Pathology

Ilie M, Falk AT, Butori C, Chamorey E, Bonnetaud C, Long E, Lassalle S, Zahaf K, Vénissac N, Mouroux J, Cohen C, Brambilla E, Marquette CH, Hofman V, Hofman P.

2016 Dec;29(12):1552-1564

Pathologists and liquid biopsies: to be or not to be? Virchows Arch.

Hofman P, Popper HH. 

2016 Dec;469(6):601-609.

High expression of TRF2, SOX10, and CD10 in circulating tumor microemboli detected in metastatic melanoma patients. A potential impact for the assessment of disease aggressiveness. Cancer Med.

Long E, Ilie M, Bence C, Butori C, Selva E, Lalvée S, Bonnetaud C, Poissonnet G, Lacour JP, Bahadoran P, Brest P, Gilson E, Ballotti R, Hofman V, Hofman P. 

2016 Jun;5(6):1022-30.
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2015

Genetic and pharmacological inactivation of the purinergic P2RX7 receptor dampens inflammation but increases tumor incidence in a mouse model of colitis-associated cancer. Cancer Res.
Hofman P, Cherfils-Vicini J, Bazin M, Ilie M, Juhel T, Hébuterne X, Gilson E, Schmid-Alliana A, Boyer O, Adriouch S, Vouret-Craviari V. 

2015 Mar 1;75(5):835-45.

Immunohistochemistry as a potential tool for routine detection of the NRAS Q61R mutation in patients with metastatic melanoma. J Am Acad Dermatol.
Ilie M, Long-Mira E, Funck-Brentano E, Lassalle S, Butori C, Lespinet-Fabre V, Bordone O, Gay A, Zahaf K, Poissonnet G, Lacour JP, Bahadoran P, Ballotti R, Gros A, Dutriaux C, Saiag P, Merlio JP, Vergier B, Emile JF, Hofman V, Hofman P.

2015 May;72(5):786-93
2015 Jan;26(1):238-44
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2014

Clinical value of circulating endothelial cells and of soluble CD146 levels in patients undergoing surgery for non-small cell lung cancer. Br J Cancer.
Ilie M, Long E, Hofman V, Selva E, Bonnetaud C, Boyer J, Vénissac N, Sanfiorenzo C, Ferrua B, Marquette CH, Mouroux J, Hofman P.

2014 Mar 4;110(5):1236-43

Detection of circulating tumor cells from lung cancer patients in the era of targeted therapy: promises, drawbacks and pitfalls. Curr Mol Med.
Hofman V, Ilie M, Long E, Guibert N, Selva E, Washetine K, Mograbi B, Mouroux J, Vénissac N, Reverso-Meinietti J, Milano G, Mazières J, Marquette CH, Paterlini-Bréchot P, Hofman P.

2014 May;14(4):440-56

Public-private relationships in biobanking: a still underestimated key component of open innovation. Virchows Arch.
Hofman P, Bréchot C, Zatloukal K, Dagher G, Clément B. 

2014 Jan;464(1):3-9
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2013

Diagnostic value of immunohistochemistry for the detection of the BRAFV600E
mutation in primary lung adenocarcinoma Caucasian patients.
Ann Oncol.
Ilie M, Long E, Hofman V, Dadone B, Marquette CH, Mouroux J, Vignaud JM, Begueret H, Merlio JP, Capper D, von Deimling A, Emile JF, Hofman P. 

2013 Mar;24(3):742-8.

Usefulness of immunocytochemistry for the detection of the BRAF(V600E) mutation
in circulating tumor cells from metastatic melanoma patients.
J Invest Dermatol.
Hofman V, Ilie M, Long-Mira E, Giacchero D, Butori C, Dadone B, Selva E, Tanga V, Passeron T, Poissonnet G, Emile JF, Lacour JP, Bahadoran P, Hofman P. 

2013 May;133(5):1378-81.

Two panels of plasmamicroRNAs as non-invasive biomarkers for prediction of recurrence in resectable NSCLC. PLoS One.
Sanfiorenzo C, Ilie MI, Belaid A, Barlési F, Mouroux J, Marquette CH, Brest P, Hofman P.

2013;8(1):e54596.
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2012

ALK-gene rearrangement: a comparative analysis on circulating tumour cells and tumour tissue from patients with lung adenocarcinoma. Ann Oncol. 
Ilie M, Long E, Butori C, Hofman V, Coelle C, Mauro V, Zahaf K, Marquette CH, Mouroux J, Paterlini-Bréchot P, Hofman P. 

2012 Nov;23(11):2907-13.

Immunohistochemistry to identify EGFR mutations or ALK rearrangements in patients with lung adenocarcinoma. Ann Oncol.
Hofman P, Ilie M, Hofman V, Roux S, Valent A, Bernheim A, Alifano M, Leroy-Ladurie F, Vaylet F, Rouquette I, Validire P, Beau-Faller M, Lacroix L, Soria JC, Fouret P. 

2012 Jul;23(7):1738-43
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2011

Overexpression of carbonic anhydrase XII in tissues from resectable non-small cell lung cancers is a biomarker of good prognosis. Int J Cancer.
Ilie MI, Hofman V, Ortholan C, Ammadi RE, Bonnetaud C, Havet K, Venissac N, Mouroux J, Mazure NM, Pouysségur J, Hofman P. 

2011 Apr 1;128(7):1614-23.

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy. Nat Genet.
Brest P, Lapaquette P, Souidi M, Lebrigand K, Cesaro A, Vouret-Craviari V, Mari B, Barbry P, Mosnier JF, Hébuterne X, Harel-Bellan A, Mograbi B, Darfeuille-Michaud A, Hofman P. 

2011 Mar;43(3):242-5.
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